Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts

BACKGROUND: Androgen deprivation therapy improves the survival of castration-resistant prostate cancer (CRPC) patients, yet ultimately fails with debilitating side effects. Supraphysiological testosterone (SPT)-based therapy produces clinical responses with improved quality of life in a subset of pa...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Eur Urol
Κύριοι συγγραφείς: Lam, Hung-Ming, Nguyen, Holly M., Labrecque, Mark P., Brown, Lisha G., Coleman, Ilsa M., Gulati, Roman, Lakely, Bryce, Sondheim, Daniel, Chatterjee, Payel, Marck, Brett T., Matsumoto, Alvin M., Mostaghel, Elahe A., Schweizer, Michael T., Nelson, Peter S., Corey, Eva
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920609/
https://ncbi.nlm.nih.gov/pubmed/31227306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2019.05.042
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια