Yüklüyor......
AID phosphorylation regulates mismatch repair-dependent class switch recombination and affinity maturation
Activation-induced cytidine deaminase (AID) generates U:G mismatches in immunoglobulin genes that can be converted into untemplated mutations during somatic hypermutation (SHM) or DNA double-strand breaks (DSB) during class switch recombination (CSR). Null mutations in UNG and MSH2 demonstrate the c...
Kaydedildi:
| Yayımlandı: | J Immunol |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920541/ https://ncbi.nlm.nih.gov/pubmed/31757865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900809 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|