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Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells
Neuroblastoma is the most commonly diagnosed extracranial tumor in the first year of life. Approximately 9% of neuroblastoma patients present germline or somatic aberrations in the gene encoding for anaplastic lymphoma kinase (ALK). This increases in high-risk neuroblastomas, which have a 14% freque...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920469/ https://ncbi.nlm.nih.gov/pubmed/31852910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55060-7 |
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