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(-)-Epicatechin and NADPH oxidase inhibitors prevent bile acid-induced Caco-2 monolayer permeabilization through ERK1/2 modulation

Secondary bile acids promote gastrointestinal (GI) tract permeabilization both in vivo and in vitro. Consumption of high fat diets increases bile acid levels in the GI tract which can contribute to intestinal permeabilization and consequent local and systemic inflammation. This work investigated the...

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Bibliografski detalji
Izdano u:Redox Biol
Glavni autori: Wang, Ziwei, Litterio, M. Corina, Müller, Michael, Vauzour, David, Oteiza, Patricia I.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920094/
https://ncbi.nlm.nih.gov/pubmed/31677553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101360
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