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Contrasting effects of ERK on tight junction integrity in differentiated and under-differentiated Caco-2 cell monolayers

ERK (extracellular-signal-regulated kinase) activation leads to disruption of tight junctions in some epithelial monolayers, whereas it prevents disruption of tight junctions in other epithelia. The factors responsible for such contrasting influences of ERK on tight junction integrity are unknown. T...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Aggarwal, Sudhir, Suzuki, Takuya, Taylor, William L., Bhargava, Aditi, Rao, Radhakrishna K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438673/
https://ncbi.nlm.nih.gov/pubmed/20961289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100249
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