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Cytotoxicity of paraquat in microglial cells: involvement of PKCδ- and ERK1/2-dependent NADPH oxidase

Excess production of reactive oxygen species (ROS) is an important mechanism underlying the pathogenesis of a number of neurodegenerative diseases including Parkinson’s disease (PD) which is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. Exposure to paraquat, an...

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Bibliografiska uppgifter
Huvudupphovsmän: Miller, Rebecca L, Sun, Grace Y., Sun, Albert Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084263/
https://ncbi.nlm.nih.gov/pubmed/17662968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.06.046
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