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Cytotoxicity of paraquat in microglial cells: involvement of PKCδ- and ERK1/2-dependent NADPH oxidase
Excess production of reactive oxygen species (ROS) is an important mechanism underlying the pathogenesis of a number of neurodegenerative diseases including Parkinson’s disease (PD) which is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. Exposure to paraquat, an...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084263/ https://ncbi.nlm.nih.gov/pubmed/17662968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.06.046 |
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