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Transitioning to composite bacterial mutagenicity models in ICH M7 (Q)SAR analyses
The International Council on Harmonisation (ICH) M7(R1) guideline describes the use of complementary (quantitative) structure-activity relationship ((Q)SAR) models to assess the mutagenic potential of drug impurities in new and generic drugs. Historically, the CASE Ultra and Leadscope software platf...
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| Publicado no: | Regul Toxicol Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6919322/ https://ncbi.nlm.nih.gov/pubmed/31586682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2019.104488 |
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