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Predicting opioid receptor binding affinity of pharmacologically unclassified designer substances using molecular docking

Opioids represent a highly-abused and highly potent class of drugs that have become a significant threat to public safety. Often there are little to no pharmacological and toxicological data available for new, illicitly used and abused opioids, and this has resulted in a growing number of serious ad...

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Publicat a:PLoS One
Autors principals: Ellis, Christopher R., Kruhlak, Naomi L., Kim, Marlene T., Hawkins, Edward G., Stavitskaya, Lidiya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967713/
https://ncbi.nlm.nih.gov/pubmed/29795628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197734
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