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Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules

Three quantitative structure-activity relationship (QSAR) models for predicting the affinity of mu-opioid receptor (μOR) ligands have been developed. The resulted models, exploiting the accessibility of the QSAR modeling, generate a useful tool for the investigation and identification of unclassifie...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Floresta, Giuseppe, Rescifina, Antonio, Abbate, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539757/
https://ncbi.nlm.nih.gov/pubmed/31083294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092311
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