A carregar...
Computational Design of Nanobody Binding to Cortisol to Improve Their Binding Affinity Using Molecular Docking and Molecular Dynamics Simulations
Currently, nanobody binding cortisol has been deposited in the database. Unfortunately, the affinity is still in micromolar order. Substituting hydrophobic residues in the binding pocket and utilizing CDR2 and CDR3 is the strategy to improve the affinity. A single and double substitution at position...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Department of Chemistry, Universitas Gadjah Mada
2022-03-01
|
| Colecção: | Indonesian Journal of Chemistry |
| Assuntos: | |
| Acesso em linha: | https://jurnal.ugm.ac.id/ijc/article/view/71480 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|