The Influence of Murine Genetic Background in Adeno-Associated Virus Transduction of the Mouse Brain

Adeno-associated virus (AAV) vectors have become an important tool for delivering therapeutic genes for a wide range of neurological diseases. AAV serotypes possess differential cellular tropism in the central nervous system. Although several AAV serotypes or mutants have been reported to transduce...

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Pubblicato in:Hum Gene Ther Clin Dev
Autori principali: He, Ting, Itano, Michelle S., Earley, Lauriel F., Hall, Nikita E., Riddick, Natallia, Samulski, R. Jude, Li, Chengwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919261/
https://ncbi.nlm.nih.gov/pubmed/31749390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2019.030
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