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AAV8 Virions Hijack Serum Proteins to Increase Hepatocyte Binding for Transduction Enhancement

It has been demonstrated that human serum albumin (HSA) directly interacts with AAV virions and enhances AAV transduction. Several other proteins have also been identified a potential for enhancing AAV8 liver transduction. In our study, LDL or transferrin could enhance transduction in vitro and in v...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Virology
Päätekijät: Pei, Xiaolei, He, Ting, Hall, Nikita E., Gerber, David, Samulski, R. Jude, Li, Chengwen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911186/
https://ncbi.nlm.nih.gov/pubmed/29455066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.02.007
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