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AAV8 Virions Hijack Serum Proteins to Increase Hepatocyte Binding for Transduction Enhancement
It has been demonstrated that human serum albumin (HSA) directly interacts with AAV virions and enhances AAV transduction. Several other proteins have also been identified a potential for enhancing AAV8 liver transduction. In our study, LDL or transferrin could enhance transduction in vitro and in v...
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| Publié dans: | Virology |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911186/ https://ncbi.nlm.nih.gov/pubmed/29455066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.02.007 |
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