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Lot-to-Lot Variation in Adeno-Associated Virus Serotype 9 (AAV9) Preparations
Viral vectors are complex drugs that pose a particular challenge for manufacturing. Previous studies have shown that, unlike small-molecule drugs, vector preparations do not yield a collection of identical particles. Instead, a mixture of particles that vary in capsid stoichiometry and impurities is...
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| Publicado no: | Hum Gene Ther Methods |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6919242/ https://ncbi.nlm.nih.gov/pubmed/31752530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2019.105 |
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