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Gene, Stem Cell, and Alternative Therapies for SCA 1
Spinocerebellar ataxia 1 is an autosomal dominant disease characterized by neurodegeneration and motor dysfunction. In disease pathogenesis, polyglutamine expansion within Ataxin-1, a gene involved in transcriptional repression, causes protein nuclear inclusions to form. Most notably, neuronal dysfu...
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| Vydáno v: | Front Mol Neurosci |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981596/ https://ncbi.nlm.nih.gov/pubmed/27570504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00067 |
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