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Exposure of HepaRG Cells to Sodium Saccharin Underpins the Importance of Including Non-Hepatotoxic Compounds When Investigating Toxicological Modes of Action Using Metabolomics

Metabolites represent the most downstream information of the cellular organisation. Hence, metabolomics experiments are extremely valuable to unravel the endogenous pathways involved in a toxicological mode of action. However, every external stimulus can introduce alterations in the cell homeostasis...

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Publicado en:Metabolites
Main Authors: Cuykx, Matthias, Beirnaert, Charlie, Rodrigues, Robim Marcelino, Laukens, Kris, Vanhaecke, Tamara, Covaci, Adrian
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918164/
https://ncbi.nlm.nih.gov/pubmed/31689907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9110265
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