IDENTIFICATION OF A PAN-GAMMA-SECRETASE INHIBITOR RESPONSE SIGNATURE FOR NOTCH-DRIVEN CHOLANGIOCARCINOMA

Cholangiocarcinoma (CCA) mortality rates are increasing due to rising incidence and limited curative treatment(s) for patients with advanced disease. NOTCH pathway reactivation has been reported in biliary malignancies to conflicting degrees, hindering prioritization of key therapeutic targets withi...

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Bibliografiske detaljer
Udgivet i:Hepatology
Main Authors: O’Rourke, Colm J., Matter, Matthias S., Nepal, Chirag, Caetano-Oliveira, Rui, Ton, Phuongnga T., Factor, Valentina M., Andersen, Jesper B.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918012/
https://ncbi.nlm.nih.gov/pubmed/31211856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30816
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