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The Role of Notch and Gamma-secretase Inhibition in an Ovarian Cancer Model

BACKGROUND: The Notch pathway is dysregulated in ovarian cancer. We sought to examine the role of Notch and gamma-secretase (GS) inhibition in ovarian cancer. MATERIALS AND METHODS: Established ovarian cancer cell lines were used. Quantitative polymerase chain reaction (qPCR) was used to determine t...

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Detalhes bibliográficos
Main Authors: SHAH, MONJRI M., ZERLIN, MARIELBA, LI, BLAKE Y., HERZOG, THOMAS J., KITAJEWSKI, JAN K., WRIGHT, JASON D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893696/
https://ncbi.nlm.nih.gov/pubmed/23482747
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