IDENTIFICATION OF A PAN-GAMMA-SECRETASE INHIBITOR RESPONSE SIGNATURE FOR NOTCH-DRIVEN CHOLANGIOCARCINOMA

Cholangiocarcinoma (CCA) mortality rates are increasing due to rising incidence and limited curative treatment(s) for patients with advanced disease. NOTCH pathway reactivation has been reported in biliary malignancies to conflicting degrees, hindering prioritization of key therapeutic targets withi...

Full description

Saved in:
Bibliographic Details
Published in:Hepatology
Main Authors: O’Rourke, Colm J., Matter, Matthias S., Nepal, Chirag, Caetano-Oliveira, Rui, Ton, Phuongnga T., Factor, Valentina M., Andersen, Jesper B.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918012/
https://ncbi.nlm.nih.gov/pubmed/31211856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30816
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items