The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis

Aim of this study was to investigate the activation of the IFNγ pathway in the affected liver and in the blood of patients with secondary hemophagocytic lymphohistiocytosis (sHLH). To this purpose, the mRNA expression levels of IFNG and IFNγ-inducible genes as well as Tyrosine (701)-phosphorylated s...

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Bibliographic Details
Published in:PLoS One
Main Authors: Prencipe, Giusi, Bracaglia, Claudia, Caiello, Ivan, Pascarella, Antonia, Francalanci, Paola, Pardeo, Manuela, Meneghel, Alessandra, Martini, Giorgia, Rossi, Marianna N., Insalaco, Antonella, Marucci, Giulia, Nobili, Valerio, Spada, Marco, Zulian, Francesco, De Benedetti, Fabrizio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917341/
https://ncbi.nlm.nih.gov/pubmed/31846457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226043
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