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The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis

Aim of this study was to investigate the activation of the IFNγ pathway in the affected liver and in the blood of patients with secondary hemophagocytic lymphohistiocytosis (sHLH). To this purpose, the mRNA expression levels of IFNG and IFNγ-inducible genes as well as Tyrosine (701)-phosphorylated s...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Prencipe, Giusi, Bracaglia, Claudia, Caiello, Ivan, Pascarella, Antonia, Francalanci, Paola, Pardeo, Manuela, Meneghel, Alessandra, Martini, Giorgia, Rossi, Marianna N., Insalaco, Antonella, Marucci, Giulia, Nobili, Valerio, Spada, Marco, Zulian, Francesco, De Benedetti, Fabrizio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917341/
https://ncbi.nlm.nih.gov/pubmed/31846457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226043
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