The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis

Aim of this study was to investigate the activation of the IFNγ pathway in the affected liver and in the blood of patients with secondary hemophagocytic lymphohistiocytosis (sHLH). To this purpose, the mRNA expression levels of IFNG and IFNγ-inducible genes as well as Tyrosine (701)-phosphorylated s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Prencipe, Giusi, Bracaglia, Claudia, Caiello, Ivan, Pascarella, Antonia, Francalanci, Paola, Pardeo, Manuela, Meneghel, Alessandra, Martini, Giorgia, Rossi, Marianna N., Insalaco, Antonella, Marucci, Giulia, Nobili, Valerio, Spada, Marco, Zulian, Francesco, De Benedetti, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917341/
https://ncbi.nlm.nih.gov/pubmed/31846457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226043
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