CRISPR/Cas9‐Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors

Although the lack of dystrophin expression in muscle myofibers is the central cause of Duchenne muscular dystrophy (DMD), accumulating evidence suggests that DMD may also be a stem cell disease. Recent studies have revealed dystrophin expression in satellite cells and demonstrated that dystrophin de...

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Publicat a:Stem Cells
Autors principals: Matre, Polina R., Mu, Xiaodong, Wu, Jianbo, Danila, Delia, Hall, Mary A., Kolonin, Mikhail G., Darabi, Radbod, Huard, Johnny
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Tissue‐Specific Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916636/
https://ncbi.nlm.nih.gov/pubmed/31574188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3094
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