CRISPR/Cas9‐Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors

Although the lack of dystrophin expression in muscle myofibers is the central cause of Duchenne muscular dystrophy (DMD), accumulating evidence suggests that DMD may also be a stem cell disease. Recent studies have revealed dystrophin expression in satellite cells and demonstrated that dystrophin de...

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Udgivet i:Stem Cells
Main Authors: Matre, Polina R., Mu, Xiaodong, Wu, Jianbo, Danila, Delia, Hall, Mary A., Kolonin, Mikhail G., Darabi, Radbod, Huard, Johnny
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Tissue‐Specific Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916636/
https://ncbi.nlm.nih.gov/pubmed/31574188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3094
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