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Generation and Characterization of a MYF5 Reporter Human iPS Cell Line Using CRISPR/Cas9 Mediated Homologous Recombination

Human iPS cells hold great promise for disease modeling and treatment of degenerative disorders including muscular dystrophies. Although a few research groups have used them for skeletal muscle differentiation, most were based on gene over-expression or long-term mesenchymal differentiation and retr...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wu, Jianbo, Hunt, Samuel D., Xue, Haipeng, Liu, Ying, Darabi, Radbod
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700424/
https://ncbi.nlm.nih.gov/pubmed/26729410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18759
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