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Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

It is well known that myogenic regulatory factors encoded by the Myod1 family of genes have pivotal roles in myogenesis, with partially overlapping functions, as demonstrated for the mouse embryo. Myogenin-mutant mice, however, exhibit severe myogenic defects without compensation by other myogenic f...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394914/
https://ncbi.nlm.nih.gov/pubmed/28473859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9210494
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