Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases

Por Okumura, Naoki, Kinoshita, Shigeru, Koizumi, Noriko
Publicado no J Ophthalmol (2017)

Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy

Por Okumura, Naoki, Hayashi, Ryousuke, Koizumi, Noriko
Publicado no Open Ophthalmol J (2018)

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

Por Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Publicado no PLoS One (2015)

Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

Por Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Publicado no Stem Cells Int (2017)

Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor

Por Koda, Sho, Okumura, Naoki, Kitano, Junji, Koizumi, Noriko, Tabata, Yasuhiko
Publicado no J Ophthalmol (2017)

Feasibility of a cryopreservation of cultured human corneal endothelial cells

Por Okumura, Naoki, Kagami, Takato, Watanabe, Kyoko, Kadoya, Saori, Sato, Masakazu, Koizumi, Noriko
Publicado no PLoS One (2019)

Inhibition of TGF-β Signaling Enables Human Corneal Endothelial Cell Expansion In Vitro for Use in Regenerative Medicine

Por Okumura, Naoki, Kay, EunDuck P., Nakahara, Makiko, Hamuro, Junji, Kinoshita, Shigeru, Koizumi, Noriko
Publicado em 2013

Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data

Por Tokuda, Yuichi, Okumura, Naoki, Komori, Yuya, Hanada, Naoya, Tashiro, Kei, Koizumi, Noriko, Nakano, Masakazu
Publicado no Sci Data (2020)

Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells

Por Okumura, Naoki, Kusakabe, Ayaka, Hirano, Hiroatsu, Inoue, Ryota, Okazaki, Yugo, Nakano, Shinichiro, Kinoshita, Shigeru, Koizumi, Noriko
Publicado no Sci Rep (2015)

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells

Por Polisetti, Naresh, Sorokin, Lydia, Okumura, Naoki, Koizumi, Noriko, Kinoshita, Shigeru, Kruse, Friedrich E., Schlötzer-Schrehardt, Ursula
Publicado no Sci Rep (2017)

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma

Por Yamamoto, Mayumi, Quantock, Andrew J., Young, Robert D., Okumura, Naoki, Ueno, Morio, Sakamoto, Yuji, Kinoshita, Shigeru, Koizumi, Noriko
Publicado em 2012

Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium

Por Nakahara, Makiko, Okumura, Naoki, Kay, EunDuck P., Hagiya, Michio, Imagawa, Kiwamu, Hosoda, Yuuki, Kinoshita, Shigeru, Koizumi, Noriko
Publicado em 2013

Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells

Por Numata, Ryohei, Okumura, Naoki, Nakahara, Makiko, Ueno, Morio, Kinoshita, Shigeru, Kanematsu, Daisuke, Kanemura, Yonehiro, Sasai, Yoshiki, Koizumi, Noriko
Publicado em 2014

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction

Por Okumura, Naoki, Kakutani, Kazuya, Inoue, Ryota, Matsumoto, Daiki, Shimada, Tomoki, Nakahara, Makiko, Kiyanagi, Yumiko, Itoh, Takehiro, Koizumi, Noriko
Publicado no PLoS One (2016)

Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity

Por Sotozono, Chie, Inatomi, Tsutomu, Nakamura, Takahiro, Koizumi, Noriko, Yokoi, Norihiko, Ueta, Mayumi, Matsuyama, Kotone, Kaneda, Hideaki, Fukushima, Masanori, Kinoshita, Shigeru
Publicado no Acta Ophthalmol (2014)

Ocular Surface Reconstruction With a Tissue-Engineered Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases

Por Kobayashi, Masakazu, Nakamura, Takahiro, Yasuda, Makoto, Hata, Yuiko, Okura, Shoki, Iwamoto, Miyu, Nagata, Maho, Fullwood, Nigel J., Koizumi, Noriko, Hisa, Yasuo, Kinoshita, Shigeru
Publicado no Stem Cells Transl Med (2015)

Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model

Por Okumura, Naoki, Matsumoto, Daiki, Fukui, Yuya, Teramoto, Masataka, Imai, Hirofumi, Kurosawa, Tetta, Shimada, Tomoki, Kruse, Friedrich, Schlötzer-Schrehardt, Ursula, Kinoshita, Shigeru, Koizumi, Noriko
Publicado no PLoS One (2018)

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

Por Okumura, Naoki, Hashimoto, Keisuke, Kitahara, Miu, Okuda, Hirokazu, Ueda, Emi, Watanabe, Kyoko, Nakahara, Makiko, Sato, Takahiko, Kinoshita, Shigeru, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Koizumi, Noriko
Publicado no Sci Rep (2017)

Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study

Por Koizumi, Noriko, Inatomi, Tsutomu, Suzuki, Takashi, Shiraishi, Atsushi, Ohashi, Yuichi, Kandori, Michiko, Miyazaki, Dai, Inoue, Yoshitsugu, Soma, Takeshi, Nishida, Kohji, Takase, Hiroshi, Sugita, Sunao, Mochizuki, Manabu, Kinoshita, Shigeru
Publicado no Br J Ophthalmol (2015)

A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal

Por Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy L., Young, Robert D., Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko, Quantock, Andrew J.
Publicado no J Ophthalmol (2017)