Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

PURPOSE: To investigate the effect and safety of a selective Rho kinase inhibitor, ripasudil 0.4% eye drops, on corneal endothelial cells of healthy subjects. DESIGN: Prospective, interventional case series. METHODS: In this study, 6 healthy subjects were administered ripasudil 0.4% in the right eye...

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Published in:PLoS One
Main Authors: Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569567/
https://ncbi.nlm.nih.gov/pubmed/26367375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136802
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