DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways

BACKGROUND: Aberrations in DNA methylation are widespread in colon cancer (CC). Understanding origin and progression of DNA methylation aberrations is essential to develop effective preventive and therapeutic strategies. Here, we aimed to dissect CC subtype-specific methylation instability to unders...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Epigenetics
Egile Nagusiak: Noreen, Faiza, Küng, Taya, Tornillo, Luigi, Parker, Hannah, Silva, Miguel, Weis, Stefan, Marra, Giancarlo, Rad, Roland, Truninger, Kaspar, Schär, Primo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916434/
https://ncbi.nlm.nih.gov/pubmed/31842975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0791-1
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