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Chromosomal Instability in BRAF Mutant, Microsatellite Stable Colorectal Cancers
The BRAF oncogene is mutated in 15% of sporadic colorectal cancers. Approximately half of these BRAF mutant cancers demonstrate frequent frameshift mutations termed microsatellite instability (MSI), but are diploid and chromosomally stable. BRAF wild type cancers are typically microsatellite stable...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478278/ https://ncbi.nlm.nih.gov/pubmed/23110075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047483 |
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