DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways

BACKGROUND: Aberrations in DNA methylation are widespread in colon cancer (CC). Understanding origin and progression of DNA methylation aberrations is essential to develop effective preventive and therapeutic strategies. Here, we aimed to dissect CC subtype-specific methylation instability to unders...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Noreen, Faiza, Küng, Taya, Tornillo, Luigi, Parker, Hannah, Silva, Miguel, Weis, Stefan, Marra, Giancarlo, Rad, Roland, Truninger, Kaspar, Schär, Primo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916434/
https://ncbi.nlm.nih.gov/pubmed/31842975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0791-1
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