Effective and Rapid Generation of Functional Neutrophils from Induced Pluripotent Stem Cells Using ETV2-Modified mRNA

Human induced pluripotent stem cells (hiPSCs) can serve as a versatile and scalable source of neutrophils for biomedical research and transfusion therapies. Here we describe a rapid efficient serum- and xenogen-free protocol for neutrophil generation, which is based on direct hematoendothelial progr...

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Publicado en:Stem Cell Reports
Main Authors: Brok-Volchanskaya, Vera S., Bennin, David A., Suknuntha, Kran, Klemm, Lucas C., Huttenlocher, Anna, Slukvin, Igor
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915846/
https://ncbi.nlm.nih.gov/pubmed/31708474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.10.007
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