Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Antimicrobial peptides (AMPs) are key effectors of the innate immune system and promising therapeutic agents. Yet, knowledge on how to design AMPs with minimal cross-resistance to human host-defense peptides remains limited. Here, we systematically assess the resistance determinants of Escherichia c...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Kintses, Bálint, Jangir, Pramod K., Fekete, Gergely, Számel, Mónika, Méhi, Orsolya, Spohn, Réka, Daruka, Lejla, Martins, Ana, Hosseinnia, Ali, Gagarinova, Alla, Kim, Sunyoung, Phanse, Sadhna, Csörgő, Bálint, Györkei, Ádám, Ari, Eszter, Lázár, Viktória, Nagy, István, Babu, Mohan, Pál, Csaba, Papp, Balázs
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915728/
https://ncbi.nlm.nih.gov/pubmed/31844052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13618-z
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