Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Antimicrobial peptides (AMPs) are promising antimicrobials, however, the potential of bacterial resistance is a major concern. Here we systematically study the evolution of resistance to 14 chemically diverse AMPs and 12 antibiotics in Escherichia coli. Our work indicates that evolution of resistanc...

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Pubblicato in:Nat Commun
Autori principali: Spohn, Réka, Daruka, Lejla, Lázár, Viktória, Martins, Ana, Vidovics, Fanni, Grézal, Gábor, Méhi, Orsolya, Kintses, Bálint, Számel, Mónika, Jangir, Pramod K., Csörgő, Bálint, Györkei, Ádám, Bódi, Zoltán, Faragó, Anikó, Bodai, László, Földesi, Imre, Kata, Diána, Maróti, Gergely, Pap, Bernadett, Wirth, Roland, Papp, Balázs, Pál, Csaba
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778101/
https://ncbi.nlm.nih.gov/pubmed/31586049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12364-6
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