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Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo
Cancer cells in culture rely on glutamine as an anaplerotic substrate to replenish tricarboxylic acid (TCA) cycle intermediates that have been consumed. but it is uncertain whether cancers in vivo depend on glutamine for anaplerosis. Here, following in vivo infusions of [(13)C(5)]-glutamine in mice...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6915720/ https://ncbi.nlm.nih.gov/pubmed/31844152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55718-2 |
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