Cardiolipin-deficient cells depend on anaplerotic pathways to ameliorate defective TCA cycle function

Previous studies have shown that the cardiolipin (CL)-deficient yeast mutant, crd1Δ, has decreased levels of acetyl-CoA and decreased activities of the TCA cycle enzymes aconitase and succinate dehydrogenase. These biochemical phenotypes are expected to lead to defective TCA cycle function. In this...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Biol Lipids
Main Authors: Raja, Vaishnavi, Salsaa, Michael, Joshi, Amit S., Li, Yiran, van Roermund, Carlo W T, Saadat, Nadia, Lazcano, Pablo, Schmidtke, Michael, Hüttemann, Maik, Gupta, Smiti V., Wanders, Ronald J.A., Greenberg, Miriam L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639082/
https://ncbi.nlm.nih.gov/pubmed/30731133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2019.02.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados