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Wasted TMEM16A Channels Are Rescued by Phosphatidylinositol 4,5-Bisphosphate

Recently there has been a flurry of interest in the regulation of the homo-dimeric calcium-activated chloride channel ANO1 (also known as TMEM16A) by phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P(2)). These recent studies show that upon Ca(2+) binding, PI(4,5)P(2) cooperates to maintain the cond...

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Detalhes bibliográficos
Publicado no:Cell Calcium
Main Authors: Arreola, Jorge, Hartzell, H. Criss
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913893/
https://ncbi.nlm.nih.gov/pubmed/31683182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2019.102103
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