A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer

Circulating tumor cell clusters (CTCcl) have a higher metastatic potential compared to single CTCs and predict long-term outcomes in breast cancer (BC) patients. Because of the rarity of CTCcls, molecular characterization of primary tumors that give rise to CTCcl hold significant promise for better...

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Pubblicato in:J Clin Med
Autori principali: Thangavel, Hariprasad, Angelis, Carmine De, Vasaikar, Suhas, Bhat, Raksha, Jolly, Mohit Kumar, Nagi, Chandandeep, Creighton, Chad J., Chen, Fengju, Dobrolecki, Lacey E., George, Jason T., Kumar, Tanya, Abdulkareem, Noor Mazin, Mao, Sufeng, Nardone, Agostina, Rimawi, Mothaffar, Osborne, C. Kent, Lewis, Michael T., Levine, Herbert, Zhang, Bing, Schiff, Rachel, Giuliano, Mario, Trivedi, Meghana V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912280/
https://ncbi.nlm.nih.gov/pubmed/31652963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111772
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