A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer

While G protein-coupled receptors (GPCRs) are known to be excellent drug targets, the second largest family of adhesion-GPCRs is less explored for their role in health and disease. ADGRF1 (GPR110) is an adhesion-GPCR and has an important function in neurodevelopment and cancer. Despite serving as a...

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Publicado en:FASEB J
Autores principales: Abdulkareem, Noor Mazin, Bhat, Raksha, Qin, Lanfang, Vasaikar, Suhas, Gopinathan, Ambily, Mitchell, Tamika, Shea, Martin J., Nanda, Sarmistha, Thangavel, Hariprasad, Zhang, Bing, De Angelis, Carmine, Schiff, Rachel, Trivedi, Meghana V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218746/
https://ncbi.nlm.nih.gov/pubmed/34110646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100070R
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