Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways

Influenza A virus (IAV) and influenza B virus (IBV) cause yearly epidemics with significant morbidity and mortality. When zoonotic IAVs enter the human population, the viral hemagglutinin (HA) requires adaptation to achieve sustained virus transmission. In contrast, IBV has been circulating in human...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Laporte, Manon, Stevaert, Annelies, Raeymaekers, Valerie, Boogaerts, Talitha, Nehlmeier, Inga, Chiu, Winston, Benkheil, Mohammed, Vanaudenaerde, Bart, Pöhlmann, Stefan, Naesens, Lieve
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912116/
https://ncbi.nlm.nih.gov/pubmed/31597759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01430-19
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