Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways

Influenza A virus (IAV) and influenza B virus (IBV) cause yearly epidemics with significant morbidity and mortality. When zoonotic IAVs enter the human population, the viral hemagglutinin (HA) requires adaptation to achieve sustained virus transmission. In contrast, IBV has been circulating in human...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Laporte, Manon, Stevaert, Annelies, Raeymaekers, Valerie, Boogaerts, Talitha, Nehlmeier, Inga, Chiu, Winston, Benkheil, Mohammed, Vanaudenaerde, Bart, Pöhlmann, Stefan, Naesens, Lieve
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912116/
https://ncbi.nlm.nih.gov/pubmed/31597759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01430-19
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