The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways

The high transmissibility of SARS-CoV-2 is related to abundant replication in the upper airways, which is not observed for the other highly pathogenic coronaviruses SARS-CoV and MERS-CoV. We here reveal features of the coronavirus spike (S) protein, which optimize the virus towards the human respira...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Laporte, Manon, Raeymaekers, Valerie, Van Berwaer, Ria, Vandeput, Julie, Marchand-Casas, Isabel, Thibaut, Hendrik-Jan, Van Looveren, Dominique, Martens, Katleen, Hoffmann, Markus, Maes, Piet, Pöhlmann, Stefan, Naesens, Lieve, Stevaert, Annelies
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061995/
https://ncbi.nlm.nih.gov/pubmed/33886690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009500
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