Parallel signaling through IRE1α and PERK regulates pancreatic neuroendocrine tumor growth and survival

Master regulators of the unfolded protein response (UPR), IRE1alpha and PERK promote adaptation or apoptosis depending on the level of endoplasmic reticulum (ER) stress. While the UPR is activated in many cancers, its effects on tumor growth remain unclear. Derived from endocrine cells, pancreatic n...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Moore, Paul C., Qi, Jenny Y., Thamsen, Maike, Ghosh, Rajarshi, Peng, Justin, Gliedt, Micah J., Meza-Acevedo, Rosa, Warren, Rachel E., Hiniker, Annie, Kim, Grace E., Maly, Dustin J., Backes, Bradley J., Papa, Feroz R., Oakes, Scott A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911642/
https://ncbi.nlm.nih.gov/pubmed/31672843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1116
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky