Triple Therapy with MerTK and PD1 Inhibition plus Radiotherapy Promotes Abscopal Antitumor Immune Responses

PURPOSE: Radiotherapy (RT) traditionally has been used for local tumor control in the treatment of cancer. The recent discovery that radiotherapy can have anti-cancer effects on the immune system has led to recognition of its ability to sensitize the tumor microenvironment to immunotherapy. However,...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Caetano, Mauricio da Silva, Younes, Ahmed I., Barsoumian, Hampartsoum B., Quigley, Michael, Menon, Hari, Gao, Chan, Spires, Thomas, Reilly, Timothy P., Cadena, Alexandra P., Cushman, Taylor R., Schoenhals, Jonathan E., Li, Ailin, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911635/
https://ncbi.nlm.nih.gov/pubmed/31540976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0795
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