Assessing Bladder Cancer Risk in Type 2 Diabetes Clinical Trials: the Dapagliflozin Drug Development Program as a ‘Case Study’

per Ptaszynska, Agata, Cohen, Samuel M., Messing, Edward M., Reilly, Timothy P., Johnsson, Eva, Johnsson, Kristina
Publicat a Diabetes Ther (2015)

Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 diabetes mellitus

per Whaley, Jean M, Tirmenstein, Mark, Reilly, Timothy P, Poucher, Simon M, Saye, JoAnne, Parikh, Shamik, List, James F
Publicat 2012

Mice Lacking Natural Killer T Cells Are More Susceptible to Metabolic Alterations following High Fat Diet Feeding

per Martin-Murphy, Brittany V., You, Qiang, Wang, Hong, De La Houssaye, Becky A., Reilly, Timothy P., Friedman, Jacob E., Ju, Cynthia
Publicat 2014

Carcinogenicity Risk Assessment Supports the Chronic Safety of Dapagliflozin, an Inhibitor of Sodium–Glucose Co-Transporter 2, in the Treatment of Type 2 Diabetes Mellitus

per Reilly, Timothy P., Graziano, Michael J., Janovitz, Evan B., Dorr, Thomas E., Fairchild, Craig, Lee, Francis, Chen, Jian, Wong, Tai, Whaley, Jean M., Tirmenstein, Mark
Publicat 2014

Drug-induced Allergic Hepatitis Developed in Mice When Myeloid-Derived Suppressor Cells Were Depleted Prior to Halothane Treatment

per Chakraborty, Mala, Fullerton, Aaron M., Semple, Kenrick, Chea, Lynette S., Proctor, William R., Bourdi, Mohammed, Kleiner, David E., Zeng, Xiangbin, Ryan, Pauline M., Dagur, Pradeep K., Berkson, Julia D., Reilly, Timothy P., Pohl, Lance R.
Publicat a Hepatology (2015)

Triple Therapy with MerTK and PD1 Inhibition plus Radiotherapy Promotes Abscopal Antitumor Immune Responses

per Caetano, Mauricio da Silva, Younes, Ahmed I., Barsoumian, Hampartsoum B., Quigley, Michael, Menon, Hari, Gao, Chan, Spires, Thomas, Reilly, Timothy P., Cadena, Alexandra P., Cushman, Taylor R., Schoenhals, Jonathan E., Li, Ailin, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W.
Publicat a Clin Cancer Res (2019)

Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors

per Schalper, Kurt A., Carleton, Michael, Zhou, Ming, Chen, Tian, Feng, Ye, Huang, Shu-Pang, Walsh, Alice M., Baxi, Vipul, Pandya, Dimple, Baradet, Timothy, Locke, Darren, Wu, Qiuyan, Reilly, Timothy P., Phillips, Penny, Nagineni, Venkata, Gianino, Nicole, Gu, Jianlei, Zhao, Hongyu, Perez-Gracia, Jose Luis, Sanmamed, Miguel F., Melero, Ignacio
Publicat a Nat Med (2020)

Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma

per Barsoumian, Hampartsoum B, Ramapriyan, Rishab, Younes, Ahmed I, Caetano, Mauricio S, Menon, Hari, Comeaux, Nathan I, Cushman, Taylor R, Schoenhals, Jonathan E, Cadena, Alexandra P, Reilly, Timothy P, Chen, Dawei, Masrorpour, Fatemeh, Li, Ailin, Hong, David S, Diab, Adi, Nguyen, Quynh-Nhu, Glitza, Isabella, Ferrarotto, Renata, Chun, Stephen G, Cortez, Maria Angelica, Welsh, James
Publicat a J Immunother Cancer (2020)