Drug-induced Allergic Hepatitis Developed in Mice When Myeloid-Derived Suppressor Cells Were Depleted Prior to Halothane Treatment

Clinical evidence suggests that many cases of serious idiosyncratic drug-induced liver injury (I-DILI) are mediated by the adaptive immune system in response to hepatic drug-protein adducts, also referred to as drug-induced allergic hepatitis (DIAH), but detailed mechanistic proof has remained elusi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hepatology
Κύριοι συγγραφείς: Chakraborty, Mala, Fullerton, Aaron M., Semple, Kenrick, Chea, Lynette S., Proctor, William R., Bourdi, Mohammed, Kleiner, David E., Zeng, Xiangbin, Ryan, Pauline M., Dagur, Pradeep K., Berkson, Julia D., Reilly, Timothy P., Pohl, Lance R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528654/
https://ncbi.nlm.nih.gov/pubmed/25712247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27764
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