Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma

Molecular characterization of lung squamous cell carcinoma (LUSC), one of the major subtypes of lung cancer, has not sufficiently improved its non-stratified treatment strategies over decades. Accumulating evidence suggests that lineage-specific transcriptional regulators control differentiation sta...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Sato, Takashi, Yoo, Seungyeul, Kong, Ranran, Sinha, Abhilasha, Chandramani-Shivalingappa, Prashanth, Patel, Ayushi, Fridrikh, Maya, Nagano, Osamu, Masuko, Takashi, Beasley, Mary Beth, Powell, Charles A., Zhu, Jun, Watanabe, Hideo
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911633/
https://ncbi.nlm.nih.gov/pubmed/31551362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2132
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