Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma

Molecular characterization of lung squamous cell carcinoma (LUSC), one of the major subtypes of lung cancer, has not sufficiently improved its non-stratified treatment strategies over decades. Accumulating evidence suggests that lineage-specific transcriptional regulators control differentiation sta...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sato, Takashi, Yoo, Seungyeul, Kong, Ranran, Sinha, Abhilasha, Chandramani-Shivalingappa, Prashanth, Patel, Ayushi, Fridrikh, Maya, Nagano, Osamu, Masuko, Takashi, Beasley, Mary Beth, Powell, Charles A., Zhu, Jun, Watanabe, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911633/
https://ncbi.nlm.nih.gov/pubmed/31551362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2132
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