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Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis

Cigarette-smoke (CS) exposure and aging are the leading causes of chronic obstructive pulmonary disease (COPD)-emphysema development, although the molecular mechanism that mediates disease pathogenesis remains poorly understood. Our objective was to investigate the impact of CS exposure and aging on...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Vij, Neeraj, Chandramani-Shivalingappa, Prashanth, Van Westphal, Colin, Hole, Rachel, Bodas, Manish
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866380/
https://ncbi.nlm.nih.gov/pubmed/27413169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00110.2016
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