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Master Autophagy Regulator Transcription Factor EB Regulates Cigarette Smoke-Induced Autophagy Impairment and Chronic Obstructive Pulmonary Disease–Emphysema Pathogenesis

Aims: Recent studies have shown that cigarette smoke (CS)-induced oxidative stress impairs autophagy, resulting in aggresome-formation that correlates with severity of chronic obstructive pulmonary disease (COPD)-emphysema, although the specific step in autophagy pathway that is impaired is unknown....

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Principais autores: Bodas, Manish, Patel, Neel, Silverberg, David, Walworth, Kyla, Vij, Neeraj
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510670/
https://ncbi.nlm.nih.gov/pubmed/27835930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6842
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